Molecular machinery in cardiac mitochondria reacts to metabolic stress in unexpected way

In a recent study published in Nature Communications, researchers at Karolinska Institutet report that the molecular ...
Nature

ATP binding to neighbouring subunits and intersubunit allosteric coupling underlie proteasomal ATPase function

The primary functions of the proteasome are driven by a highly allosteric ATPase complex. ATP binding to only two subunits in this hexameric complex triggers substrate binding, ATPase–20S association ...
Phys.org

New study examines ATP synthase at acidic state to reveal how the enzyme functions

A collaborative effort led by Stuti Sharma, Ph.D., Assistant Professor in the Department of Biochemistry & Cell Biology at Stony Brook University, resulted in a promising study toward a better ...
Phys.org

Insights into the formation of ATP synthase: A new important function of the folding helper Hsp70

"The ATP synthase protein complex consists of a spinning rotor driven by the back transport of protons into the mitochondrial matrix. This part is connected to the enzyme's catalytic head by a stalk, ...
technologynetworks

Acidic Insights into ATP Synthase Function

A collaborative effort led by Stuti Sharma, PhD, Assistant Professor in the Department of Biochemistry & Cell Biology at Stony Brook University, resulted in a promising study toward a better ...
Nanowerk

Adenosine Triphosphate (ATP): The Universal Energy Currency of Living Cells

What is Adenosine Triphosphate (ATP)? Adenosine triphosphate (ATP) is a nucleotide that serves as the primary energy carrier in all known living organisms. It consists of three components: the ...
Nature

Extracellular ATP elicits DORN1-mediated RBOHD phosphorylation to regulate stomatal aperture

In addition to acting as a cellular energy source, ATP can also act as a damage-associated molecular pattern in both animals and plants. Stomata are leaf pores that control gas exchange and, therefore ...