Due to significant developments in neuroscience techniques, researchers are now able to selectively exploit neural systems in conscious animals, through emerging methods called chemogenetics and ...

Epilepsy is one of the most common neurological diseases in the world. International health institutions estimate that over 50 million people worldwide are affected by it. Seizures, the hallmark ...

For years, pharmaceutical companies have cut back on drug development that targeted neurological conditions. After trials and failures in dementia, depression, and epilepsy, companies learned that ...

These results make it imperative for researchers to do proper controls with clozapine, and indicate that they should change their protocols altogether. “I’m glad I don’t own stock in CNO,” says Scott ...

A neuron in the mouse brain expressing a chemogenetic receptor (red) surrounded by neurons (blue) that lack the receptor. [C. J. Magnus et al./Science 2019] Scientists at the Howard Hughes Medical ...

Chemogenetics Provides a Noninvasive Tool for Precise Control of Neural Circuits The phrase “mind-control drugs” probably conjures up some terrifying images, but in the case of chemogenetics, it could ...

What the scientists had was a lab version of The Dog That Didn’t Bark — or, if Sherlock Holmes were chronicling the experiment, The Mice That Didn’t Freeze. One at a time, the 20 mice went into a ...

The future of pain management may combine genetic engineering and small-molecule drugs. Coda Biotherapeutics, a South San Francisco-based start-up, has raised $19 million in series A financing to ...

Researchers have come up with a new method to control brain cells in live animals using specially designed receptor proteins that respond to the drug varenicline. While drug-responsive receptors have ...