“[...] this suggests a model where the accumulation of DNA damage with aging impairs vascular function ultimately resulting in [cardiovascular disease].” Advanced ...
Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...
The cohesin subunit Scc1 returns and reconstitutes the complex with Smc1–Smc3 in late mitosis upon DNA double-strand breaks, although it does not participate in homologous recombination-driven MAT ...
The team discovered that the protein PARP1 becomes an underwater superglue and creates a special healing zone that holds the loose DNA ends together and lets the DNA repair begin. The discovery ...
A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 19, entitled, "Reduction of double-strand DNA break ...
Tea will be served at 12:45 p.m., immediately preceding the seminar.
The protooncoprotein N-Myc, which is overexpressed in approximately 25% of neuroblastomas as the consequence of MYCN gene amplification, has long been postulated to regulate DNA double-strand break ...
A new research paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma ...
New research reveals how bowhead whales live more than 200 years and rarely develop cancer, offering promising insights into ...
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