Did you know that genes can mask and alter the effects of other genes? Could this process, called epistasis, be a key to understanding complex conditions like Alzheimer’s disease and diabetes?

Epistasis has been used to describe a number of phenomena, including the functional interaction between genes, the genetic outcome of mutations acting within the same genetic pathway, and the ...

Jim Manzi has a long post up on epistasis, that is, gene-gene interactions: We could call this process of competing algorithms struggling to find the best solution as fast as possible "meta-evolution" ...

A team of researchers from Skoltech and their Russian and U.S. colleagues have gathered two dozen mushrooms of the species Schizophyllum commune and analyzed their DNA, gaining insights into mutations ...

Explore the Shifting Balance Theory and its role in understanding epistasis and evolutionary genetics. , an anthology of recent research on the issue of epistasis and its relationship to evolution.^2 ...

Imagine your doctor calls you to discuss the results of your genetic testing. They tell you your results indicate you are highly likely to develop Alzheimer's disease. But not to worry, because they ...

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic, has undergone genomic mutations, which have led to the ...

Euan Ashley's lab explores the intricate interactions of gene variants. Tiny "typos," or genetic mutations, can sneak into segments of DNA. Many of these are harmless, but some can cause health ...

Why evolutionary genetics does not always add up / Edmund D. Brodie III -- Beyond the average : the evolutionary importance of gene interactions and variability of epistatic effects / Patrick C.