E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible. “It’s as ...

Bacterial gene regulation is a finely tuned process essential for cellular adaptation and survival. Central to this regulation are nucleoid-associated proteins (NAPs), which not only compact the ...

DNA methylation in bacteria, primarily involving the addition of methyl groups to adenine or cytosine residues, constitutes a pivotal epigenetic mechanism that modulates gene expression without ...

At first glance, an Escherichia Coli (E. Coli) bacterium looks a bit like a Cheeto, with the same puffy cylindrical shape. But it is a Cheeto lookalike with incredible immune defenses. Behind the ...

Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation. Bacterial infections cause millions of deaths each year, with the global threat ...

Bacterial infections can be difficult to treat, and by 2019, they were causing over a million deaths per year. The problem of antibiotic resistance is expected to get worse in the coming years.

Antibiotic resistance is widely recognized as one of the most urgent public health challenges of the twenty first century.

Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression. LacI is a tetrameric protein, using two dimers to bind two specific, ...

Antibiotic resistance is widely recognized as one of the most urgent public health challenges of the twenty first century.

Multidrug-resistant bacteria pose a major threat to human health. Manipulation of bacterial genes at the transcriptional level is a potential strategy to fight antibiotic-resistant bacterial ...