Tier 1 aberrations, which are classified as those having well-established prognostic, diagnostic, or therapeutic relevance according to guidelines set by medical societies such as WHO, NCCN and ICC, ...

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

April 14, 2025 – Genome Research (https://genome.org) publishes a second special issue highlighting advances in long-read sequencing applications in biology and medicine. In this second Special Issue, ...

In cancer care, every day that passes can cost a life. First Ascent Biomedical is racing against that clock. By testing a patient's live cancer cells outside the body, the company reveals how their ...