DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

In our bodies, there are trillions of cells. From white blood cells to skin cells, each type has its own specific function which helps us perform tasks and survive. But what makes up these cells and ...

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators.

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.

Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed down during ...

While in the big scheme of things DNA is still something we only recently found out about, a huge amount of research has gone into this subject, so it can be confidently said that experts really have ...