EurekAlert!

Four generations help science explore genome mutation rate

The William H. Foege Genome Sciences Building at the University of Washington School of Medicine in Seattle contains laboratories, sequencers, computational facilities, and other resources for ...
Phys.org

Somatic and germline mutation rates covary linearly across ciliates and mammals, study finds

In a study published in Current Biology on August 14, Prof. Miao Wei's team at the Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences and Prof. Zhang Jianzhi's team at the University ...
GEN

Multi-Platform Sequencing Study of Four Generations Sheds Light on Mutation Rates

Using sequencing instruments from multiple vendors, scientists from the University of Utah Health, the University of Washington, PacBio, and elsewhere have developed what they claim is the most ...
ascopubs.org

Use of Cigarette-Smoking History to Estimate the Likelihood of Mutations in Epidermal Growth Factor Receptor Gene Exons 19 and 21 in Lung Adenocarcinomas

Multicenter Phase I Study of Repeated Intratumoral Delivery of Adenoviral p53 in Patients With Advanced Non–Small-Cell Lung Cancer EGFR exon 19 and 21 mutation status was determined in 265 tumor ...
Medical Xpress

Fertility treatments linked to higher mutations than natural conception in mice

Mice pups conceived with in vitro fertilization (IVF) in the lab have slightly increased rates of DNA errors, or mutations, compared to pups conceived naturally, a new study on artificial reproductive ...