In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

The main steps involved and limitations of microarray analysis will be encountered. Two stages can be distinguished in microarray experiments: a pre-microarray experiment phase (tissue handling) and ...

Microarrays, including genome tiling microarrays, are exceptionally powerful tools for querying diverse genomic features, including mapping gene expression and structure, analyzing polymorphisms, ...

Phase I and Pharmacologic Study of Oral ZD9331, A Novel Nonpolyglutamated Thymidylate Synthase Inhibitor, in Adult Patients With Solid Tumors ABSTRACT: Aberrant gene expression is critical for tumor ...

The research community's rapid acceptance of microarrays notwithstanding, technical challenges remain. Biochip developers continue to grapple with these issues while upgrading their offerings and ...

Paris, France, Friday 13 June 2008: A new DNA microarray chip can predict severe disability and remission in patients with rheumatoid arthritis (RA), as presented today at EULAR 2008, the Annual ...

This is a preview. Log in through your library . Abstract We demonstrate the use of a chromosomal walk (or "tiling path") printed as DNA microarrays for mapping protein-DNA interactions across large ...

Microbial comparative genomics provides insights into gene function, bacterial speciation and evolutionary relationships. In the August 14 Proceedings of the National Academy of Sciences, Murray et al ...