A ribozyme found by accident selectively repairs broken RNA, suggesting early life could have preserved its genetic code ...

In most modern cells, DNA stores the genetic blueprint, and proteins replicate, repair and build from those blueprints. At ...

In most modern cells, DNA stores the genetic blueprint, and relies on proteins to replicate, repair and build from those ...

Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers. RNA interference (RNAi) ...

RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and ...

Evidence of a newly identified mechanism of horizontal gene transfer raises important questions about how evolution works.

RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions (IDR), reports a new study from the Institute of Science, Tokyo, Japan. Using ...

Researchers from Skoltech and other science centers in Russia have developed a reporter system—a tool for screening potential ...

Plain-language definition: RNA therapy is medicine that works by adding, blocking, or changing RNA instructions inside cells. More formally, it is a class of treatment that uses RNA molecules, or ...

RNA editing denotes post-transcriptional modifications that alter nucleotide sequences within RNA molecules, thereby expanding the diversity and regulatory potential of the transcriptome. The most ...

Bacterial regulatory RNAs, notably small non-coding RNAs (sRNAs) and riboswitches, orchestrate gene expression at the post-transcriptional level. These molecules interact with target mRNAs to modulate ...