A research team led by the A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a method to accurately and ...

Roche has put forward a new approach to genetic analysis, which it describes as sequencing-by-expansion—a proprietary method that pulls apart the DNA molecule and amplifies the signal of each ...

A*STAR scientists have developed a new method to directly and efficiently read DNA containing non-standard “letters” (bases) ...

November 20, 2024 – Genome Research (https://genome.org) publishes a special issue highlighting advances in long-read sequencing applications in biology and medicine. In this first of two Special ...

A new study shows that long-read sequencing has the potential to improve the rate of diagnosis while reducing the time to diagnosis from years to days -- in a single test and at a much lower cost. One ...

DNA methylation is a critical epigenetic mechanism in numerous biological processes, including gene regulation, development, ageing and the onset of various diseases such as cancer. Studies of ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis ...

Researchers including those at the University of Tokyo have made a surprising discovery hiding in people's mouths: Inocles, giant DNA elements that had previously escaped detection. These appear to ...

At a time when large-scale human genome analysis was not yet common, the Tohoku Medical Megabank Organization (ToMMo) ...

Researchers set a new world record for the fastest DNA sequencing, completing a whole genome in under four hours—a breakthrough with potential for faster, targeted care.