The most frequent DNA lesions (8-oxoguanine, thymine glycol, dihydrothymine, dU) (De Bont and van Larebeke, 2014) are removed from the genome by the BER (Kim and Wilson, 2012) (Figure 1). This repair ...
A researcher has made a discovery that alters our understanding of how the body's DNA repair process works and may lead to new chemotherapy treatments for cancer and other disorders. Researchers ...
Abasic sites in DNA are generated by hydrolysis of the N-glycosidic bond that connects the base to the deoxyribose sugar. This occurs either spontaneously, particularly in the case of purines 1, or ...
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