A designed polypeptide scaffold contains a surface immobilization domain and a target capture domain for flexible protein arraying. 'Microarray' might just be the hottest buzzword in biology today.

EMBL scientists have improved a protein analysis technique, significantly expanding its use and making it 100 times faster.

Researchers have developed a method to evaluate the folding stability of a million proteins simultaneously. DNA libraries were used to generate protein -- DNA complexes that were treated with enzymes ...

The new cell-free protein crystallization (CFPC) method includes direct protein crystallization and is a major headway in the field of structural biology. This technique will enable the analysis of ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

Protein degraders, which induce the protein degradation of target proteins, are expected to be the "next-generation drugs" because they can remove disease-related proteins from cells. Protein ...

In a paper recently published in Nature Communications, the HUN-REN-ELTE Protein Modeling Research Group (Institute of Chemistry) has laid the foundations for a mathematical method, allowing the ...

Since their inception in 1995, DNA microarrays have become the icon of the genomics revolution. Everyone with any interest has become familiar with the images of precise rows and columns of colored ...

Planar waveguide (PWG) technology (right) has the advantage over conventional epifluorescence excitation (left) for surface-confined assays in that only surface-bound fluorphores respond to the ...

Stay up to date on the latest science with Brush Up Summaries. Using genomics, researchers map exomes and whole genomes and identify genetic markers and gene variants. However, one key limitation of ...

The sequencing phase of the human genome project is now near completion, but then what? An even harder challenge remains — to identify the structures and functions of all proteins encoded in the ...