Researchers at MIT have just developed a new lipid nanoparticle that super-enhances the effectiveness of the mRNA vaccine in ...
This manuscript reports on the application of ribosome profiling (EZRA-seq and eRF1-seq) combined with massively parallel reporter assays to identify and characterize a GA-rich element associated with ...
The authors investigated the epigenetic mechanisms regulating the differentiation of circulating monocytes that infiltrate the CNS and adopt microglia-like characteristics. The work is useful to the ...
Researchers at Stockholm University have extracted and sequenced the oldest known RNA molecules in the world ( Cell 2025, DOI: 10.1016/j.cell.2025.10.025). The ancient RNA (aRNA) comes from skin and ...
In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers. This study aimed to ...
Expression profiling is a universal tool, with a range of applications that benefit from the accurate determination of differential gene expression. To allow normalization using endogenous transcript ...
Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...
HHS Secretary Robert F. Kennedy Jr.'s decision to cancel $500 million in funding and wind down development of mRNA vaccines is a disastrous one -- especially with the looming threat of an H5N1 avian ...
The U.S. Department of Health and Human Services announced on Tuesday that it will cancel $500 million worth of projects dedicated to designing messenger RNA (mRNA) vaccines for pandemic preparedness.
Abstract: Having the five-year survival rate of approximately 5%, currently, the fourth leading reason for cancer-related deaths is pancreatic cancer. Previously, various works have concluded that ...