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  1. Tumor initiation and early tumorigenesis: molecular mechanisms …

    Jun 19, 2024 · Recently, researchers are emphasizing the mechanisms of environmental tumor risk factors and epigenetic alterations that are profoundly influencing early clonal expansion …

  2. Understanding Cancer Development | AACR Cancer Progress …

    Understanding the Path to Cancer Development In this section, you will learn: Cancer is a collection of diseases that are characterized by unchecked cell multiplication. Basic research …

  3. Carcinogenesis - Wikipedia

    Carcinogenesis Cancers and tumors are caused by a series of mutations. Each mutation alters the behavior of the cell somewhat. Carcinogenesis, also called oncogenesis or tumorigenesis, …

  4. Development and Spread of Cancer - The Merck Manuals

    The first step in cancer development is initiation, in which a change in a cell’s genetic material (a mutation) primes the cell to become cancerous. The change in the cell’s genetic material may …

  5. What Is Cancer? - NCI

    Oct 11, 2021 · Explanations about what cancer is, how cancer cells differ from normal cells, and genetic changes that cause cancer to grow and spread.

  6. New discovery in cancer signaling reveals a potential path to more ...

    1 day ago · A large, multi-institution study led by a Brown University physician-scientist could have important implications for the development of new classes of cancer therapeutics.

  7. Cancer Development - CancerQuest

    Cancer Development Introduction Simply put, cancer is the result of unregulated cell division. Cancer cells divide when they are not supposed to, don't stop dividing when they are …

  8. Tumor Development, Immunology and Progression Laboratory

    The Tumor Development, Immunology & Progression Lab of Peter Storz, Ph.D., at Mayo Clinic studies cell signaling, tumorigenesis in pancreatic cancer & breast cancer.

  9. How does cancer start? - Cancer Research UK

    Cancer starts with changes in one cell or a small group of cells in the body. The changes make cells start to grow and multiply too much.

  10. Cancer associated fibroblasts in cancer development and therapy

    Mar 28, 2025 · Cancer-associated fibroblasts (CAFs) are key players in cancer development and therapy, and they exhibit multifaceted roles in the tumor microenvironment (TME). From their …